All animals are born with a set of instincts, or innate behaviors, and our main questions are how complex behaviors are organized in the nervous system and how they are programmed during development. For this, the chemosensory system would be one of the most excellent models. Smell and taste are known to be important for sensing predators, selecting mates as well as finding food. We would like to trace the neuronal pathways that mediate a complex instinctive behavior such as feeding, from sensory input through to motor output. We are using the fruit fly as a model system to study chemosensation.
Education
(Ph.D.) 2000 ~ 2003 Department of Biology, Yonsei University
Experience
2012 - Present Professor, Dept. of Biological Sciences, Sungkyunkwan University
2012 - 2018 Associate Professor, Dept. of Biological Sciences, Sungkyunkwan University
2008 - 2012 Assistant Professor, Dept. of Biological Sciences, Sungkyunkwan University
2003 - 2008 Postdoc, MCDB, Yale University
Journal Articles
(2023)
Nanoporous MoS<sub>2</sub> Field-Effect Transistor Based Artificial Olfaction: Achieving Enhanced Volatile Organic Compound Detection Inspired by the <i>Drosophila</i> Olfactory System.
ACS NANO.
17,
21
(2021)
Taste sensing and sugar detection mechanisms in Drosophila larval primary taste center.
ELIFE.
10,
e67844
(2021)
Spatiotemporal organization of enteroendocrine peptide expression in Drosophila.
JOURNAL OF NEUROGENETICS.
35,
4
(2021)
Identification and characterization of GAL4 drivers that mark distinct cell types and regions in the Drosophila adult gut.
JOURNAL OF NEUROGENETICS.
35,
1
(2020)
Cellular Basis of Bitter-Driven Aversive Behaviors in Drosophila Larva.
ENEURO.
7,
2
(2018)
Drosophila Gr64e mediates fatty acid sensing via the phospholipase C pathway.
PLOS GENETICS.
14,
2
(2017)
Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds.
NATURE COMMUNICATIONS.
8,
(2017)
Ionotropic Receptor 76b Is Required for Gustatory Aversion to Excessive Na+ in Drosophila.
MOLECULES AND CELLS.
40,
10
(2017)
Deciphering the Genes for Taste Receptors for Fructose in Drosophila.
MOLECULES AND CELLS.
40,
10
(2017)
Involvement of a Gr2a-Expressing Drosophila Pharyngeal Gustatory Receptor Neuron in Regulation of Aversion to High-Salt Foods.
MOLECULES AND CELLS.
40,
5
(2017)
Field-Effect Transistor Biosensor Platform Fused with Drosophila Odorant-Binding Proteins for Instant Ethanol Detection.
ACS APPLIED MATERIALS INTERFACES.
9,
16
(2016)
A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons.
NATURE PROTOCOLS.
11,
12
(2016)
A Pair of Pharyngeal Gustatory Receptor Neurons Regulates Caffeine-Dependent Ingestion in Drosophila Larvae.
FRONTIERS IN CELLULAR NEUROSCIENCE.
10,
(2016)
A Systematic Analysis of Drosophila Regulatory Peptide Expression in Enteroendocrine Cells.
MOLECULES AND CELLS.
39,
4
(2016)
Maintenance of Membrane Integrity and Permeability Depends on a Patched-Related Protein in Caenorhabditis elegans.
GENETICS.
202,
4
(2016)
A subset of enteroendocrine cells is activated by amino acids in the Drosophila midgut.
FEBS LETTERS.
590,
4
(2016)
TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.
PLOS GENETICS.
12,
1
Conference Paper
(2021)
Gal4 drivers for distinct cell types and regions of the Drosophila gut.
2021 virtual meeting on NEUROBIOLOGY OF DROSOPHILA.
UNITED STATES
(2020)
Involvement of a Pair of Drosophila Larval Pharyngeal Gustatory Receptor Neuron in Amino Acid Sensing.
한국분자세포생물학회 정기학술대회.
KOREA, REPUBLIC OF
(2020)
The Drosophila Genetic Reference Panel (DGRP) as a Tool for Studying Gustatory Receptors.
한국분자세포생물학회 정기학술대회.
KOREA, REPUBLIC OF
(2018)
Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds.
2018 Fall Symposium (Korean Society for Chemical Senses and Ingestive Behavior).
KOREA, REPUBLIC OF
(2018)
The organization of enteroendocrine cells in Drosophila.
Neurofly 2018 (17th European Drosophila Neurobiology Conference).
POLAND
(2018)
Molecular and behavioral analysis of gustatory receptor neurons in Drosophila larvae.
21st Annual Meeting of the Korean Society for Brain and Neural Sciences.
KOREA, REPUBLIC OF
(2017)
A systematic analysis of Drosohila Regulatory Peptide Expression in Enteroendocrine cells.
The Inaugural Asia-Pacific Drosophila Neurobiology Conference.
CHINA
(2017)
Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds.
ECRO (European Chemoreception Research Organization) 2017.
UNITED KINGDOM
(2015)
Molecular and behavioral analysis of gustatory receptor neurons in Drosophila larvae.
Brain Conference 2015.
KOREA, REPUBLIC OF
(2015)
Behavioral analysis of gustatory receptor neurons in bitter sensing in Drosophila larvae.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Distinct functional populations of Drosophila enteroendocrine cells.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Function of gustatory receptors in Drosophila enteroendocrine cells.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Functional analysis of gustatory receptor neurons as feeding modulators in Drosophila larvae.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Organization of enteroendocrine cells in the Drosophila midgut.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Screening for novel elements involved in bitter sensing in Drosophila larvae.
3rd Asia-Pacific Drosophila Research Conference.
CHINA
(2015)
Molecular and behavioral analysis of gustatory receptor neurons in pharyngeal organs as modulators of feeding in Drosophila larvae.
56th Annual Drosophila Research Conference.
UNITED STATES
(2014)
Behavioral analysis of bitter taste perception in Drosophila larvae.
Cold Spring Harbor Asia Conference, Neurobiology: Diverse Species and Conserved Principles.
CHINA
(2014)
Organization of neuropeptide genes in Drosophila enteroendocrine cells.
Cold Spring Harbor Asia Conference, Neurobiology: Diverse Species and Conserved Principles.
CHINA
(2013)
Heterogeneous expression of Drosophila gustatory receptors and neuropeptides in enteroendocrine cells.
2nd Asia-Pacific Drosophila Research Conference.
KOREA, REPUBLIC OF
(2013)
Molecular organization of the taste system in the Drosophila larva.
2nd Asia-Pacific Drosophila Research Conference.
KOREA, REPUBLIC OF
